Determination of Hecogenin in Mouse Blood by UPLC-MS/MS and Applied to a Pharmacokinetic Study.
Hecogenin, a steroidal sapogenin from agave plants, exhibits anti-inflammatory, anti-tumor, gastroprotective, and diuretic activities. A sensitive ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for quantifying hecogenin in mouse whole blood using swertisi...