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Author

Qiong-Fang Ruan

2 papers indexed here

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Open access Sep 2026

IGK Suppresses Keloid Fibroblast Activation Through Modulation of MDM2 Expression and p53 Signaling.

Keloids are intricate fibroproliferative disorders characterized by sustained fibroblast activation, excessive deposition of extracellular matrix, and dysregulated wound-healing responses. This study explored the therapeutic effects and underlying mechanisms of Isoginkgetin (IGK) in keloid fibroblasts (KFbs) and a huma...

Zi-Qing Ye, Feng Liu, Huan-Cheng Tang et al. · 0 citations
Open access Sep 2026

Targeting SIRT3 dysfunction with a sprayable honokiol hydrogel for diabetic burn wound repair

Background Diabetic burn wound healing is impaired by persistent mitochondrial oxidative stress, chronic inflammation, bacterial infection, and defective tissue regeneration. Although honokiol possesses antioxidant and anti-inflammatory properties, its therapeutic potential is limited by poor local retention. Moreover,...

Min Li, Xue-Dong Yu, Huan-Tao Hu et al. · 0 citations

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