IGK Suppresses Keloid Fibroblast Activation Through Modulation of MDM2 Expression and p53 Signaling.
Keloids are intricate fibroproliferative disorders characterized by sustained fibroblast activation, excessive deposition of extracellular matrix, and dysregulated wound-healing responses. This study explored the therapeutic effects and underlying mechanisms of Isoginkgetin (IGK) in keloid fibroblasts (KFbs) and a huma...