Melatonin-Hydrogel Delivery Systems for Effective Treatments of Periodontitis: Translational Perspectives from Material Designs to Clinical Applications
Periodontitis is a chronic infectious disease characterized by progressive destruction of periodontal supporting tissues. Conventional treatments, including mechanical therapy and local drug delivery, are hindered by poor drug retention, burst release, and short duration of action. Melatonin (MT), an endogenous indolea...