Large-scale transcriptome analysis reveals KIF20A as a novel indicator of cisplatin resistance in high-grade serous ovarian cancer.
BACKGROUND Accurately assessing chemosensitivity to drugs such as cisplatin is crucial for optimizing outcomes of high-grade serous ovarian carcinoma (HGSOC) patients. Developing prediction models and identifying biomarkers can assist differentiate chemotherapy-sensitive from chemotherapy-resistant subtypes. METHODS...