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Author

Qiu-Di Deng

2 papers indexed here

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Open access Oct 2026

SOX4 drives ferroptosis resistance of non-small cell lung cancer by regulating PI3K/AKT/SREBP1/SCD1 signaling axis

Non-small cell lung cancer (NSCLC) remains a challenging disease due to its high heterogeneity and the lack of effective treatment strategies. Ferroptosis, a recently identified form of regulated cell death driven by the accumulation of lipid hydroperoxides, has emerged as a promising therapeutic strategy in NSCLC. W...

Xue-Ping Lei, Jie-Yao Liu, Ji-Hong Gu et al. · 0 citations
Open access Sep 2026

A fungal-derived benzothiazole derivative overcomes osimertinib resistance in NSCLC by targeting SCD1

6-(2-hydroxyethyl) benzo[d]thiazol-4-ol (HBT) is identified as a promising therapeutic candidate for overcoming osimertinib resistance in NSCLC and SCD1 is suggested as a potential target for combating such resistance.

Bo-Yin Li, Yuan-Yu Ke, Jin-Hua Zhu et al. · 0 citations

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