3-Epicabraleadiol inhibits LmrS protein of Staphylococcus aureus isolated from cow mastitis and enhances antibiotic susceptibility.
Staphylococcus aureus (S. aureus) is a major pathogen of bovine mastitis, and its antimicrobial resistance poses challenges to livestock and public health. The lincomycin resistance protein (LmrS) contributes significantly to this resistance. However, many efflux pump inhibitors (EPIs) are limited clinically due to tox...