DNA Logic-Gated Biosensing of the Tumor Microenvironment for Multicomponent Profiling and Programmable Molecular Decision-Making
The tumor microenvironment (TME) is spatially and temporally heterogeneous, limiting the specificity of single-biomarker strategies for resolving complex tumor states. The sequence programmability and predictable base pairing of DNA allow multiple biological inputs to be recognized, logically processed, and translated...