Author

Qiu-Ye Luo

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Open access Oct 2026

Curcumin analogue FLLL32 induces ferroptosis by targeting the STAT3-GPX4/SLC40A1 axis in colorectal cancer

A STAT3-GPX4/SLC40A1-dependent mechanism underlying the anti-CRC activity of FLLL32 is defined to support further investigation of STAT3-associated ferroptosis regulation as a potential therapeutic vulnerability in CRC.

Tong Wu, Meng-Qiu Hao, Qiu-Ye Luo et al. · Molecular Biomedicine · 0 citations

Open access Jul 2026

Targeting HASPIN-mediated H3T3 phosphorylation disrupts an epigenetic-kinesin axis to suppress colorectal cancer mitotic progression.

The findings identify the HASPIN/H3T3ph-KDM5B-H3K4me3-KIF axis as a targetable antimitotic pathway and support therapeutic inhibition of HASPIN/H3T3ph as a potential strategy for CRC.

Tong Wu, Yaguang Zhang, Si-Cheng Liu et al. · Molecular Cancer · 0 citations