Up-Regulation of FBXO17 Promotes Ferroptosis and Suppresses the Stemness of Prostate Cancer Cells Through Wnt/β-Catenin Pathway.
As a critical component of E3 ubiquitin ligase complexes, FBXO17 exhibits either tumor-promoting or tumor-suppressing in a variety of tumors, but its biological function and molecular mechanism in prostate cancer (PCa) are still unclear. FBXO17 expression in PCa cell lines and normal prostate epithelial cells (RWPE-1)...