A comprehensive three-dimensional epigenomic analysis of four main glial populations, including vRG, oRG, oligodendrocyte precursor cells and microglia, from the mid-gestational human neocortex identifies cell-type-specific candidate cis-regulatory elements (cCREs) and validated their regulatory function using transgen...
Ian R. Jones, Li Wang, M. Kosicki et al.· Nature· 0 citations
It is demonstrated that expression of SNHG1, SNHG12, and SNHG30 in EWS cells contributes to the maintenance of cancer cell fitness via their role in intron-processed snoRNAs encoded in SNHG1 and SNHG12.
Marcela Briones-Martin-Del-Campo, Alex G. Lee, Truc Dinh et al.· NAR Cancer· 0 citations
Language is a defining trait of our species, and disruptions in language acquisition can have profound consequences to the individuals affected. Uncovering the neurodevelopmental basis of this complex trait requires detailed molecular and cellular insights into the neocortical areas that support linguistic abilities. H...
Juan Moriano, Tanzila Mukhtar, J. Lee et al.· bioRxiv· 0 citations
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