An N-Salicyloyl Tryptamine Derivative (Compound 18) Improves Spermatogenic Impairment in Obese Mice via Regulating Insulin Resistance and Enhancing Sertoli Cell Glycolysis.
OBJECTIVE This study aimed to investigate the therapeutic potential of compound 18, an N-salicyloyl tryptamine derivative with established anti-neuroinflammatory and neuroprotective properties, in ameliorating male reproductive dysfunction induced by high-fat diet (HFD) in obese mice and to elucidate the underlying mec...