Aug 2026
Captopril Enables the Inhibition of tRNA-Mediated Tau Aggregation.
Using in vitro reconstitution and high-resolution imaging, tRNA is identified as a major inducer of tau aberrant aggregation and captopril effectively inhibits both general and tRNA-induced tau aggregation, positioning CAP as a potential therapeutic candidate.
Bo-Ru Peng, Quan Deng, Xiao-Hua Zhu et al.
· Langmuir · 0 citations