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Author

Quan-Shun Li

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Review Aug 2026

DNAzymes: a promising tool in gene therapy.

The growing demand for precise and effective gene therapy has driven the extensive exploration of nucleic acid therapeutics. DNAzymes are catalytically active single-stranded DNA molecules with high programmability and substrate-recognition specificity, and they have been considered as promising tools for gene therapy....

Yang Li, Haojie Sun, Muxi Han et al. · 0 citations
Open access Aug 2026

Tailored Covalent Organic Frameworks Enable the Encapsulation of Living Cells to Produce Rare Ginsenoside.

A scalable whole-cell immobilization platform through in situ assembly of recombinant Escherichia coli expressing Sulfolobus solfataricus β-glycosidase with three covalent organic frameworks that enabled the immobilization of various prokaryotic and eukaryotic microbes, demonstrating favorable universality.

Feng-Mei Liu, Shan Zhang, Shan-Rong Wei et al. · 0 citations
Open access Aug 2026

Evolution-inspired multi-objective Bayesian optimization for protein engineering

EvoMOBO is established as a modular framework for multi-objective protein engineering using experimental or mechanism-derived labels using simulation-derived mechanistic descriptors, with experiments reserved for final validation.

Kai Wen, Sirui Wang, Yixin Sun et al. · 0 citations

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