Author

Quan Zhang

2 papers indexed here

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Open access Oct 2026

MD‐1 Deficiency Mitigates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation via cGAS‐STING Dependent Pathway in Macrophages

Findings reveal that MD‐1 promotes pro‐inflammatory (M1‐like) macrophage polarisation in atherosclerosis by inhibiting NLRP3 inflammasome activation via a cGAS‐STING dependent pathway and suggest that MD‐1 neutralisation could be a potential therapeutic strategy for atherosclerosis management.

Fang Zhao, Zhi-Li Jin, Zhi-Wei Cai et al. · Cell Proliferation · 0 citations

Open access Aug 2026

PLCE1 exacerbates the development of atherosclerosis by driving endothelial dysfunction and macrophage inflammation via targeting CTNNB1

The infiltration of macrophages and the inflammatory response they mediate, which are initiated by endothelial dysfunction, are pivotal in both the initiation and progression of atherogenesis. Phospholipase C epsilon 1 (PLCE1) is significantly involved in cardiovascular diseases, in part due to its regulation of va...

Wen-Lin Cheng, Yu-Fang Shi, Quan Zhang et al. · Cell Death Discovery · 0 citations