Review
Oct 2026
The unfolded protein response in precision oncology: from mechanisms to therapeutic opportunities.
The unfolded protein response (UPR) is a fundamental stress pathway coopted in cancer, and it is thought to drive adaptation, tumor progression, and therapeutic resistance. While the analysis of 'single-effector' biomarkers within the tumor microenvironment often fails to capture its spatial, temporal, and cellular com...
Quentin Bourgery, D. Doultsinos, A. Galmiche et al.
· Trends in Molecular Medicine · 0 citations