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Author

Qun Tang

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Jul 2026

A xanthone derivative MGS-3, confers protection against Staphylococcus aureus infection through SarA-mediated inhibition of alpha-hemolysin expression.

Results establish SarA suppression as MGS-3's primary anti-virulence mechanism, and MGS-3 represents a promising candidate for anti-staphylococcal drug development, targeting virulence rather than bacterial viability to potentially curb resistance evolution.

Han Bai, Yuehan Zhou, Wen-Chong Ye et al. · 0 citations

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