5-Nitrothiazol-Clofibric Acid Analogs as Potent Agents Against Nitazoxanide-Resistant Giardia lamblia: Modulation of Glycolytic Genes and Molecular Dynamics Studies
Giardiasis remains a significant global health issue, and its treatment is increasingly hampered by the emergence of drug resistance and cross-resistance between nitroimidazoles and nitazoxanide. In this study, we evaluated the in vitro antigiardial activity, cytotoxicity, and potential mechanisms of action of seven st...