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Author

R. Barr

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3 papers indexed here

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Open access Sep 2026

One-year progression of CT emphysema subtypes predict lung function decline: SPIROMICS.

One-year progression of CT emphysema subtypes predicted accelerated FEV₁ decline, supporting their potential use as intermediate endpoints in COPD trials and evaluating associations between one-year QCT measure changes and FEV₁ decline from visits two through five.

Emilia A. Hermann, E. Hoffman, Elsa D. Angelini et al. · 0 citations
Sep 2026

Systemic Platelet Activation and Respiratory Exacerbations, Pulmonary Symptoms, and Mortality among Current and Former Smokers in SPIROMICS.

RATIONALE Platelet activation is elevated in chronic obstructive pulmonary disease (COPD) and associated with self-reported respiratory symptoms. Observational studies link the antiplatelet drug aspirin to lower exacerbation rates and fewer symptoms. However, it is unknown if platelet activation predicts incident respi...

A. Fawzy, N. Hansel, N. Putcha et al. · 0 citations
Open access Jul 2026

Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed.

This work fine-mapped UK Biobank-derived genome-wide association study (GWAS) signals from 164 traits and identified e/sQTL colocalizations for 10,611 GWAS signals, including 7096 that colocalize with secondary e/sQTLs.

Peter Orchard, T. Blackwell, L. Kachuri et al. · 0 citations

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