Development, Characterization, and Preclinical Evaluation of Curcumin-Loaded Solid Lipid Nanoparticles for Enhanced Antiviral Delivery Against Zika Virus Infection.
The Zika virus (ZIKV), a neurotropic flavivirus, poses a significant global health threat due to its association with severe congenital malformations. The absence of approved antivirals necessitates novel therapeutic approaches. Curcumin, a natural polyphenol from Curcuma longa, exhibits potent anti-inflammatory and br...