Background: Carbapenem-resistant Enterobacteriaceae (CRE) prevalence has been increasing in Saudi Arabia, posing a significant public health concern. Antimicrobial stewardship programs (ASPs) play an important role in reducing resistance by ensuring appropriate antibiotic use. Our study aimed to assess the appropriaten...
L. I. Alnajjar, Taif A. Alahmari, Shahad A. Almutairi et al.· Antibiotics· 0 citations
Quinoline-Thiazolidinedione-2,4-Dione demonstrated strong antihyperglycemic and antihypertriglyceridemic activities in zebrafish models, supported by in silico validation.
ElShimaa Ahmed Mohamed Abousaada, A. Galal-Khallaf, K. Mohammed-Geba et al.· Pharmaceuticals· 0 citations
The combined biochemical, cellular, and computational findings support the proposed involvement of the EGFR/PI3K/mTOR signaling pathway in its antiproliferative activity and identify DNA gyrase as a potential antibacterial target.
Hagar S. El-Hema, Esraa M. Adel, W. El-Dougdoug et al.· Pharmaceutics· 0 citations
This integrated ML-to-simulation workflow prioritizes structurally novel candidate hits with predicted ALK inhibitory activity and provides an effective strategy for scaffold discovery and hit prioritization.
M. Haque, Q. M. Jamal, K. Ahmad et al.· Pharmaceuticals· 0 citations
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