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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

R. Burkhart

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2 papers indexed here

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Sep 2026

Abstract B016: MHC-II expressing pancreatic tumor cells alter macrophage polarization through VEGFA-NRP1 signaling

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy characterized by an immunosuppressive tumor microenvironment (TME) that limits the efficacy of immunotherapies. Tumor-associated macrophages (TAMs) represent a major cellular component of the TME and play a critical role in sustaining immunosuppres...

T. Lopez-Vidal, Jacob T. Mitchell, Kylie Belanger et al. · 0 citations
Aug 2026

Clinical, genomic, and spatial transcriptomic features of pancreatic adenosquamous carcinoma support subtype-specific therapeutic strategies.

PURPOSE Pancreatic adenosquamous carcinoma (ASQ) is a rare variant with poorly defined clinical and molecular features compared to conventional pancreatic ductal adenocarcinoma (PDAC). This study aimed to characterize the clinical outcomes, genomic landscape, and spatial transcriptomic architecture of ASQ. EXPERIMENT...

S. Haldar, Meredith Wetzel, Jia-Yun Lu et al. · 0 citations

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