Author

R. Collet-Vidiella

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Open access Aug 2026

Big tau and brain-derived tau reveal peripheral and central nervous system involvement in neuropathies

INTRODUCTION: Biomarkers for monitoring disease activity and treatment response in peripheral neuropathies remain limited. Big tau, a high-molecular-weight isoform of tau, is predominantly expressed in the peripheral nervous system (PNS). We investigated serum levels of big tau, brain-derived tau (BD-tau), and neurofil...

L. Martín-Aguilar, F. González-Ortiz, H. Zetterberg et al. · medRxiv · 0 citations

Open access Aug 2026

Methodological insights and clinical outcomes in ALS and FTLD: lessons from the SPIN cohort

Amyotrophic lateral sclerosis and frontotemporal lobar degeneration constitute a clinico‐genetic‐neuropathological continuum with marked heterogeneity and large, multimodal cohorts are needed to advance biomarker discovery and precision medicine.

Á. Carbayo, J. Turon-Sans, D. Alcolea et al. · Alzheimer's & Dementia · 0 citations