Open access
Sep 2026
Serum metabolomics identifies ganglioside dysregulation and pyruvate dehydrogenase complex–related metabolic disturbances in pediatric drug-resistant epilepsy
Despite advances in epilepsy management, the exact causes of epilepsy remain unclear, and diagnostic biomarkers are still lacking. Besides, about one-third of cases involve drug-resistant epilepsy (DRE). This study employed untargeted metabolomics to identify potential metabolic signatures in the sera of ped...
Eman Y. Abu-rish, Reem H. Almalki, Amira T. Masri et al.
· Frontiers in Pediatrics · 0 citations