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R. Dimova

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#diffusion models Open access Oct 2026

Single-protein diffusion in micrometer-size vesicles is governed by viscosity, surface charge, and membrane interactions

Giant unilamellar vesicles (GUVs) are a powerful model system for studying protein dynamics in cell-sized compartments with a precisely tunable physicochemical environment. Here, we apply Single-Molecule Displacement Mapping (SMdM) to quantify how luminal viscosity, ionic strength, membrane lipid composition, and prote...

Jelmer Coenradij, Dmitrii Linnik, Kristine Postmus et al. · 0 citations
Open access Oct 2026

Giant Vesicle Platform for Synthetic Endoplasmic Reticulum Networks

The endoplasmic reticulum (ER) is a membrane-bound organelle found in all eukaryotic cells. This organelle has a fascinating morphology, which involves a network of membrane nanotubes and three-way junctions connecting three nanotubes. Previous reconstitution studies were based on proteo-liposomes with a size of 100 to...

Cade Vallero, Shreya Pramanik, Tsu-Wang Sun et al. · 0 citations
Review Open access Sep 2026

Electric-field manipulation of giant vesicles: new frontiers in membrane electromechanics.

Giant unilamellar vesicles (GUVs) are a powerful model system whose response to electric fields constitutes a strategy to directly assess membrane material properties. In the last few years, the field has advanced in both conceptual scope and experimental precision. Electric-field manipulation of GUVs remains a versati...

R. Dimova, E. Sabri · 0 citations

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