Open access
Aug 2026
Topographic-prognostic gradients of cortical hypometabolism in temporal lobe epilepsy
A hypometabolic gradient is identified in TLE, which covaries with cytoarchitectonic organization, microstructural changes, and hippocampal-neocortical interactions and provides a biologically grounded framework for precise surgical planning, emphasizing that targeting severe hypometabolism may optimize prognosis.
J. Mo, F. Fadaie, J. Lam et al.
· medRxiv · 0 citations