Feasibility of First-line Lomustine-Temozolomide (CCNU/TMZ) in Elderly Patients with MGMT-methylated Glioblastoma: A Multicenter Retrospective Cohort Study
The CeTeG/NOA-09 trial showed improved survival with lomustine (CCNU) plus temozolomide (TMZ) over TMZ alone in O6-methylguanine-DNA-methyltransferase (MGMT) promoter-methylated glioblastoma patients aged 18-70 years. Data on feasibility, tolerability and outcomes in patients over 70 receiving this regimen are la...