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Review Sep 2026

Exercise-only interventions and exercise-based multidomain lifestyle interventions to promote cognitive function in older adults without dementia: a systematic review and meta-analysis.

OBJECTIVE To assess the effect of exercise training as a single intervention (ie, Exercise-Only) and exercise combined with other lifestyle interventions (ie, Exercise-Plus) on executive functions, memory and processing speed of older adults living without dementia. DESIGN We performed a systematic review with pairwi...

Rebeca Hernández-Gamboa, Jammy Zou, J. Oh et al. · 0 citations
Open access Oct 2026

Exercise and white matter hyperintensities: a randomized clinical trial

Subcortical vascular cognitive impairment (SVCI) is a risk factor for dementia. White matter hyperintensity (WMH) lesions are considered a hallmark of SVCI. We investigated the impact of progressive resistance exercise training (RT) on WMH in individuals with SVCI. This 12-month, single-blinded, proof-of-concept ran...

N. C. Boa Sorte Silva, R. Tam, W. Alkeridy et al. · 0 citations
Sep 2026

Resistance training and depressive symptoms in subcortical vascular cognitive impairment: secondary results of a randomised clinical trial.

OBJECTIVES Cerebral small vessel disease (CSVD) is associated with depressive symptoms. Exercise may reduce depressive symptoms for people with CSVD. We examined the effects of progressive resistance training (PRT) on depressive symptoms among adults with CSVD and mild cognitive impairment (ie, subcortical vascular cog...

R. Falck, Cindy K. Barha, R. Stein et al. · 0 citations

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