BACKGROUND
TTMV-HPV DNA testing is prognostic during post-treatment surveillance of HPV-associated oropharyngeal squamous cell carcinoma (OPSCC), but the significance of testing before conventional 3-month response assessment remains unclear.
METHODS
We retrospectively analyzed 332 patients across 8 US sites with bio...
Scott A. Roof, J. Jabalee, E. Rettig et al.· Head and Neck· 0 citations
Head and neck squamous cell carcinoma (HNSCC) has exceptionally high recurrence rates, exceeding 50%, contributing to mortality and morbidity. This recurrence rate is proposed to be due to field cancerization, a phenomenon where tumor-adjacent “field” tissue that appears histologically normal harbors molecular changes...
Claire B. Mills, Yin Huang, Chan-Mi Lee et al.· bioRxiv· 0 citations
BACKGROUND
Tumor tissue-modified viral (TTMV) human papillomavirus (HPV) DNA testing has high diagnostic and surveillance performance in HPV-associated oropharyngeal squamous cell carcinoma, but its utility in HPV-associated non-oropharyngeal (non-OP) head and neck squamous cell carcinoma (HNSCC) is not well defined....
Peter V. Cooke, Daniel O. Kraft, Susmita Chennareddy et al.· Head and Neck· 0 citations
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