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R. Foo

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Open access Aug 2026

PP2Acα regulates the Hippo-YAP signaling axis to promote cardiac regeneration and alleviate myocardial infarction.

PP2Acα is identified as a critical phosphatase that promotes neonatal cardiac regeneration by directly dephosphorylating YAP and activating the Hippo-YAP signaling axis, uncovering a previously unrecognized regulatory mechanism controlling cardiomyocyte proliferation and highlighting a potential therapeutic target for...

Anhui Wang, Boyang Qin, M. Lee et al. · 1 citation

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