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Author

R. Freitas-Junior

3 papers indexed here

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Open access 2026

TROFUSE-032: a phase 3, randomized study of pembrolizumab plus sacituzumab tirumotecan or chemotherapy followed by pembrolizumab plus chemotherapy for early-stage triple-negative breast cancer or hr+/her2– breast cancer

Introduction: Trophoblast cell surface antigen 2 (TROP2) is highly expressed in triple-negative breast cancer (TNBC) and is associated with poor prognosis. Current standard of care for high-risk, early-stage TNBC is neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab after surgery. The same a...

R. Freitas-Júnior, P. Schmid, Jing Wei et al. · 0 citations
Open access 2026

Adiponectin levels and clinical-demographic associations in breast cancer: a cross-sectional analysis

Background: Obesity and overweight in women with breast cancer have been increasing significantly, affecting two-thirds of cancer survivors. Adipocytes produce and release adiponectin, however, in general, the greater an individual’s body fat mass is, the lower their adiponectin levels are. Adiponectin is an adipokine...

V. D. L. Rosa, R. Alves, Anderson Garcia Silva et al. · 0 citations
Open access Oct 2026

Breast cancer screening based on clinical breast examination performed by community health workers: study protocol for a randomized clinical trial. ITABERAÍ Project / ReBEC n° RBR-39vm2nd.

OBJECTIVE The ITABERAÍ project evaluates whether breast cancer screening based on clinical breast examination (CBE) performed by community health workers (CHWs) can reduce advanced breast cancer and mortality. METHODS This prospective, phase III, cluster-randomized controlled trial includes women aged ≥40 years using...

R. Freitas-Júnior, D. Rodrigues, Rosangela da Silveira Corrêa et al. · 0 citations

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