Background: Major spine surgery carries an inherent risk of hemodynamic instability due to prone positioning, significant blood loss, and the strict necessity to maintain adequate spinal cord perfusion. Hemodynamic management mainly relies on a reactive approach, treating hypotension only after it occurs, which increas...
Gianluigi Cosenza, Marco Fiore, R. Giurazza et al.· Journal of Clinical Medicine· 0 citations
Background: Abdominal sepsis is associated with profound pharmacokinetic (PK) alterations that make standard beta-lactam dosing regimens potentially inadequate in critically ill patients. Increased volume of distribution, hypoalbuminemia, augmented renal clearance (ARC), acute kidney injury (AKI) and the PK complexity...
R. Giurazza, Gianluigi Cosenza, Marco Fiore et al.· Journal of Clinical Medicine· 0 citations
Background Optimal anesthetic selection is critical for recovery and patient outcomes in ambulatory surgery. This systematic review and meta‐analysis compares propofol‐based total intravenous anesthesia (TIVA) with sevoflurane in adults undergoing outpatient procedures, focusing on randomized evidence published since 2...
I. Šitum, R. Giurazza, Martina Perić Šitum et al.· Anesthesiology Research and...· 0 citations
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