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Review Open access Sep 2026

Digital pathology, image analysis, and artificial intelligence in liver disease.

Advances in digital pathology, image analysis, and artificial intelligence (AI) are rapidly transforming how pathologists and researchers interact with tissue samples and enable the development of diagnostic tools that harness high-resolution whole-slide images; these advances are in turn creating new opportunities for...

C. McGenity, D. Treanor, T. Slavik et al. · 0 citations
Preprint Sep 2026

Computationally Efficient Pathology Segmentation using Knowledge Distillation from Foundation Models

Distillation consistently improves student performance over supervised training alone, producing state-of-the-art or near state-of-the-art results with substantially fewer parameters and up to ten-fold higher inference throughput than foundation-model-based segmentation networks.

Jia-Qi Lv, Yi-Jie Zhu, Saki Okada et al. · 0 citations
Open access Aug 2026

A microbiota-responsive polyfunctional cytotoxic CD4⁺ T-cell state promotes mucosal inflammation in ulcerative colitis

Ulcerative colitis (UC) is characterised by chronic colonic inflammation with marked heterogeneity in disease severity and therapeutic outcomes. Here, we define a spatially organised, polyfunctional cytotoxic CD4⁺ T-cell state associated with mucosal inflammation and adverse therapeutic outcomes in UC. Integrating ex v...

John P Thomas, S. H. Kottoor, Jonathan W. Lo et al. · 0 citations

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