Open access
Sep 2026
Transcription factor clusters enhance gene expression in vivo without modulating bursting dynamics.
Phase separation drives key cellular processes, yet the role transcription factor condensates play in gene regulation remains contested. Evidence comes primarily from in vitro experiments, leaving it largely unknown how these structures regulate transcription in vivo. To address this knowledge gap, we used cutting-edge...
Emilia Cadar, Anthony Birnie, Richard Marsman et al.
· Molecules and Cells · 0 citations