R. Gupta

Spatiotemporal clustering of tuberculosis notifications in Nepal during the COVID-19 pandemic and subsequent recovery: A national space-time scan analysis, 2019-2024

The COVID-19 pandemic substantially disrupted tuberculosis (TB) prevention, diagnosis, and treatment services worldwide. Despite increased TB notifications in Nepal during the post-pandemic recovery period, the geographic distribution and temporal clustering of notifications remain poorly understood. This study examine...

Defining use cases for biomarkers and tests across tuberculosis infection, disease and treatment: An international consensus and prioritisation exercise

Background Translation of tuberculosis (TB) biomarker and diagnostic research into tools that improve patient and public health outcomes has been slow, partly because no internationally agreed framework exists defining the use cases that new biomarkers and tests should address. We aimed to identify, validate, and prior...

Complex intra-host SARS-CoV-2 evolution following monoclonal antibody pre-exposure prophylaxis