Author

R. Hamoudi

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Open access Sep 2026

Pathology-Guided Transcriptomic Profiling of Prostate Cancer Identifies Grade-Associated Proliferative and Immune Signatures in a MENA Cohort

Simple Summary Prostate cancer is a heterogeneous disease, and molecular markers that reflect tumor grade progression remain limited. In this study, we analyzed gene expression changes across benign, low-grade, and high-grade prostate cancer tissues using a pathology-guided transcriptomic approach in a Middle East and...

Ranyah Al-Hakm, A. Altaie, R. Alhamidi et al. · Cancers · 0 citations

Review Open access Sep 2026

Neurobiological mechanisms and brain network dysfunction in major depressive disorder: an integrative review

Major depressive disorder (MDD) is a prevalent and disabling psychiatric disorder characterized by persistent mood disturbances, cognitive impairments, and significant systemic consequences. Despite its substantial clinical burden, diagnosis remains challenging because current approaches rely largely on subjective symp...

D. Iskakova, Burcu Yener, A. Kamzanova et al. · Frontiers in Integrative Neu... · 0 citations

Open access Aug 2026

Cooperative Modular Representation Learning for Lung Adenocarcinoma Survival Prediction from Transcriptomic and Clinical Data

Cooperative Modular Representation Learning (CMRL), an uncertainty-gated multimodal framework that dynamically regulates inter-modality information flow based on sample-level epistemic uncertainty estimated via Evidential Deep Learning (EDL), is presented.

Sundus M. Jasim, Nabil Hezil, A. Bouridane et al. · bioRxiv · 0 citations