The onset of improved data interoperability required as a result of the 21st Century Cures Act, 92% Health Information Exchange coverage, and lessons learned from European pharmaceutical risk-sharing models present innovative and timely opportunities for the U.S. to adopt pharmaceutical value-based contracting (VBC), w...
Urvisha Jain, Srinidhi Polkampally, Arnav Ajay Jadav et al.· Value in Health· 0 citations
A mutation in the estrogen receptor alpha gene (ESR1m) following first-line treatment with endocrine therapy in hormone receptor-positive metastatic breast cancer occurs in nearly half of patients. Detection of this mutation prior to radiologic progression using circulating tumor DNA (ctDNA)-based monitoring is an emer...
Bridget M. Flavin, C. Tweed, J. Evans et al.· Journal of Managed Care & Sp...· 0 citations
Practical, experience-informed considerations are supplemented by an opinion-based consensus workflow model designed to provide clinicians with a flexible framework for implementing ctDNA-based ESR1m monitoring during first-line care for ER+, HER2– aBC.
Y. Abdou, Amber Cipriani, Trevor Feinstein et al.· The Oncologist· 0 citations
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