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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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R. Hollis

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Open access Sep 2026

APOBEC3 Knockout in Lentiviral Packaging Cells Improves Therapeutic Transgene Sequence Fidelity.

Lentiviral vectors are a well-established method of delivering transgenes into target cells. Lentiviral vectors have a strong efficacy and safety profile, but transgene fidelity remains an area of concern. Loss of function mutations within the integrated transgene may reduce therapeutic efficacy. Gain of function mutat...

Annika Mittelhauser, R. Patel, Alex B. Costa et al. · 0 citations

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