Repurposing Pramlintide in Colorectal Cancer: Mechanistic Insights into Metabolic Reprogramming, p53 Signaling, and Chemosensitivity in HCT-116 and HT-29 Cell Lines
Colorectal cancer (CRC) is one of the most fatal cancers in the world; acquired chemoresistance and an increasing prevalence of early-onset illness make treatment limited. This review investigates pramlintide, which is used in diabetes management, as a potential for repurposing in CRC treatment. According to the in vit...