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Review Sep 2026

Exploring the Antimicrobial Potential of Benzimidazole-based Compounds in Medicinal Chemistry: Advances and Perspectives.

INTRODUCTION The urgent need for novel antimicrobials to combat antibiotic resistance highlights benzimidazole derivatives as highly promising candidates. Over the past decade, extensive research has focused on the therapeutic potential of benzimidazole-based scaffolds in various pathological conditions, including bact...

R. Kalita, Shivani Sharma, Mukta Gupta · 0 citations
Review Open access Aug 2026

Spirooxindole Derivatives as Emerging Scaffolds in Drug Discovery: Synthetic Strategies, Structure–Activity Relationship, and Biological Activities

Spirooxindoles are a class of spirocyclic scaffolds in drug discovery, as the rigid frame and well‐defined substitution pattern can interact with various biological targets. Recent advances in synthetic methodologies, including multicomponent 1,3‐dipolar cycloadditions, organocatalytic cascades, and one‐pot protocols,...

R. Kalita, Sarbanga Bezbaruah, D. Patle · 0 citations

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