Open access
Nov 2026
A substrate-dependent mechanism of inhibition of the polyspecific multidrug efflux pump MexF from Pseudomonas aeruginosa
ABSTRACT Pseudomonas aeruginosa presents a significant challenge in both clinical and antibiotic discovery settings due to the low permeability of its cell envelope. Efflux pumps acting synergistically with the permeability barrier of the outer membrane provide efficient protection against various antibacterial agents....
Muhammad R. Uddin, J. Mehla, R. Kinthada et al.
· Antimicrobial Agents and Che... · 0 citations