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R. Kowluru

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Open access Aug 2026

Regulation of Glutathione Peroxidase 4 in Diabetic Retinopathy

Oxidative stress-mitochondrial dysfunction plays a central role in diabetic retinopathy. Glutathione peroxidase 4 (GPx4), a key antioxidant enzyme that detoxifies lipid peroxides, is inhibited in diabetes, but the mechanism underlying its inhibition is unclear. Here, we have investigated the role of ubiquitination in r...

Pooja Malaviya, R. Kowluru · 0 citations

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