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R. Ledesma-Amaro

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Open access Sep 2026

Adaptive laboratory evolution of a yeast co-culture chassis for modular bioproduction

Synthetic microbial consortia have the potential to bring novel architectures to biotechnological processes. They enable more flexible and efficient bioprocesses by reducing metabolic burden and supporting division of labour. Obligately mutualistic cross-feeding has been used to stabilise the population composition of...

Diego Ruiz-Sanchis, Javiera López-Salinas, Cinzia Klemm et al. · 0 citations
Open access Jul 2026

From Circuits to Symphonies: A Systems‐Engineering Blueprint for Multimicrobial Synthetic Biology

Synthetic biology is expanding from single‐species engineering toward the design of synthetic microbial consortia capable of distributed metabolism, coordinated behavior, and enhanced functional robustness. However, engineering frameworks derived from intracellular genetic circuits remain insufficient to capture the ec...

M. Fernández-Niño, Ludger A. Wessjohann, J. Guillamón et al. · 0 citations
Open access Jul 2026

A signal peptide-guided approach towards in situ functionalization of bacterial nanocellulose in Komagataeibacter rhaeticus.

By linking protein translocation to in situ BC functionalization, this work establishes a synthetic biology framework that supports the development of K. rhaeticus as a single-chassis platform towards the production of functionalized bioELMs.

Jenni Vannas, Amritpal Singh, Bibi Hannikainen et al. · 0 citations

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