Author

R. Loos

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Review Sep 2026

Genetics of Obesity: Discovery, Biology, Prediction, and Therapeutic Implications.

With the rise in its prevalence, obesity has become a public health threat worldwide. Understanding the genetic and biological origins of obesity is critical for discovering and implementing better prevention and treatment strategies to combat its dominance and impact on disease risk. This review summarizes current kno...

M. Babinski, R. Loos, S. Berndt et al. · Annual Review of Medicine · 0 citations

Open access Jul 2026

Cross-definition GWAS of IBS in 2.8 million individuals reveals cardiometabolic and triglyceride-linked mechanisms

This study provides the most comprehensive assessment of IBS genetics to date, demonstrating reproducible polygenic inheritance and linking IBS risk to convergent neurogastrointestinal and novel cardiometabolic mechanisms, highlight specific biological pathways and actionable mechanisms and outline translational opport...

Biagio Di Lorenzo, L. Camargo Tavares, Cristian Díaz-Muñoz et al. · Gut · 0 citations