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Author

R. Malkawi

2 papers indexed here

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Open access Sep 2026

Design and Preparation of Solid Lipid Nanoparticles to Enhance Physicochemical Properties of Etoricoxib

Objective: Etoricoxib is a selective COX-2 inhibitor with poor aqueous solubility, which may limit its dissolution behavior and physicochemical performance. This study aimed to design, prepare, and optimize etoricoxib-loaded solid lipid nanoparticles (SLNs) to enhance the physicochemical properties and in vitro release...

Ahmed R. Gardouh, R. Malkawi, Ahmed Raja Alanezi · 0 citations
Open access Jul 2026

FORMULATION AND PHYSICOCHEMICAL CHARACTERIZATION OF PACLITAXEL-LOADED PLGA NANOPARTICLES WITH ENHANCED SOLUBILITY AND IN VITRO ANTICANCER ACTIVITY

Objective: Paclitaxel is a widely used chemotherapeutic agent with extremely poor aqueous solubility (~0.3 µg/ml), which significantly limits its bioavailability and therapeutic efficacy. The present study aimed to develop and characterize paclitaxel-loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles to enhance...

R. Malkawi · 0 citations

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