Engineering vesicle-based artificial cells capable of mimicking cellular processes is a central objective in synthetic biology. However, while giant unilamellar vesicles (GUVs) have become a popular artificial cell platform, the impact of fundamental design features remains obscure. Here, we assembled GUVs composed p...
Jordi Ventura-Cobos, Ángela Morellá-Aucejo, Bastiaan C. Buddingh' et al.· ACS Synthetic Biology· 0 citations
In this work, iridium-gated Janus nanomachines are proposed as enzyme-regulated platforms for smart and autonomous drug delivery, reinforcing the potential of enzyme-controlled Janus nanomachines as multifunctional platforms integrating autonomous motion and stimulus-responsive drug delivery for advanced therapeutic ap...
Beatriz Mayol, Marta González-Jiménez, Alfredo Sánchez et al.· ACS Applied Nano Materials· 0 citations
Overall, this multifunctional nanomotor couples enhanced drug delivery with immune activation, effectively overcoming the structural and metabolic barriers of solid tumors, and represents a promising strategy for self-propelled therapeutic nanoparticles in cancer treatment.
Juan José Esteve-Moreno, Andrea Escudero, Francisco J. Hicke et al.· Journal of the American Chem...· 0 citations
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