Review
Open access
Jul 2026
Innovative Clinical Pharmacology, Modeling, and Simulation Strategies for Accelerating Rare Disease Drug Development
Examples include drug repurposing, characterizing PK/PD in early phase to inform late‐phase development, population PK analysis to guide trial dosing and label recommendations, and applying M‐PBPK to predict clinical PK in organ impairment populations.
R. Oberoi, C. Peer, Ashutosh Tripathi et al.
· Journal of clinical pharmaco... · 0 citations