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Author

R. Orlowski

2 papers indexed here

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Open access Aug 2026

Interim analysis in clinical trials: caution against premature conclusions—the SWOG multiple myeloma S0777 case study

Interim monitoring for efficacy and futility provides critical decision-making boundaries on early termination of randomized clinical trials. Such analyses can accelerate access to effective therapies and limit exposure to ineffective ones, but this must be weighed against premature closure that can risk obscuring a tr...

Emily M. Goren, R. Sexton, R. Orlowski et al. · 0 citations
Jul 2026

Single Cell Analysis of the Tumor Microenvironment Landscape Across the Disease Spectrum of Multiple Myeloma.

This study provides a comprehensive single-cell immune atlas of multiple myeloma and its precursors, offering insights into TME organization and progression, and may guide development of stage-specific or ecotype-targeted immunotherapies.

Ming-Hao Dang, Luz Yurany Moreno Rueda, Maria Jose Acevedo Calado et al. · 0 citations

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