Author

R. Patwardhan

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Review Open access Oct 2026

Spatiotemporal Redox Regulation of Cell-Cycle Progression: Dynamic Functions of Cellular Redox Regulatory Proteins

Highlights What are the main findings? Redox regulation is dynamically coordinated with cell-cycle progression through phase-specific changes in H2O2 generation, sensing, buffering, and resolution. MnSOD, peroxiredoxins, Nrf2/HO-1/NQO1, glutathione, glutaredoxins, GPXs, and the thioredoxin system perform complementary...

R. Patwardhan, S. Morjaria, G. Nandi et al. · Cells · 0 citations

Sep 2026

Peroxiredoxin 6 Silencing Remodels Lipid Metabolism and Redox Pathways to Promote Ferroptosis-Mediated Radiosensitization in Nonsmall Cell Lung Cancer.

It is shown that PRDX6 depletion enhances radiosensitivity in A549 lung cancer cells, and the underlying drivers of ferroptosis sensitivity in the PRDX6 background are identified.

Debojyoti Pal, R. Patwardhan, S. Sandur · Journal of Proteome Research · 0 citations