R. Pontarolo

Evidence mapping of concepts, methods, and outcomes in the evaluation of diagnostic and therapeutic technologies for ultra-rare diseases: a systematic scoping review.

Despite heterogeneity, there is growing convergence on prevalence-based criteria and adaptive strategies for URDs, highlighting the need for robust patient registries, international data sharing, and HTA frameworks that incorporate severity, equity, and social value.

LC-QTOF-MS Chemical Characterization, Cytotoxicity, and Antimicrobial Activity of Blue Geopropolis: An Emerging Type of Brazilian Propolis

Despite its distinct entomological origin, blue geopropolis shared chemical traits with green and red propolis while demonstrating superior Gram-positive antibacterial activity, a higher selectivity index, and potential antifungal applications against Sporothrix spp.

How is artificial intelligence being used to discover new treatments for leishmaniasis? A Scoping Review