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Jul 2026

Abstract B055: Targeting LSD1 for anti-PD1 therapy resistance mechanism in Head and Neck Cancer for future therapy

Head and Neck Squamous cell carcinoma (HNSCC) frequently exhibits resistance to anti–PD-1 immune checkpoint blockade. We asked whether dysregulated major histocompatibility complex class I (MHC-I) is a determinant of anti–PD-1 resistance, and whether targeting Lysine-specific demethylase 1 (LSD1/KDM1A) is an effe...

A. Chakraborty, R. Raut, Chumki Choudhury et al. · 0 citations

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